Multiple deaths reported in California tour bus crash

A tour bus crashed into a tractor trailer on I-10 early Sunday near Palm Springs, California.

(CNN) — A tour bus collided with a tractor-trailer near Palm Springs, California, early Sunday morning, officials said.

Up to 10 people were killed in the accident, according to CNN affiliate KESQ.

Twenty-one people were taken to the hospital, said the California Highway Patrol.

The accident happened at 5:17 a.m. local time on Interstate 10, officials said.

California Highway Patrol said the highway will be closed for several hours.