NEW YORK (CNN) -- Drug kingpin Joaquin "El Chapo" Guzman, a Houdini-like master of escape accused of running one of the world's largest drug trafficking organizations, entered a not guilty plea through his attorney at an arraignment Friday in federal court in Brooklyn.
The diminutive, clean-shaven trafficker, described by a federal official as "the most notorious criminal of modern time," was not handcuffed and wore a dark blue short-sleeved shirt and pants with white sneakers during his brief appearance in a packed courtroom.
Magistrate Judge James Orenstein asked Guzman whether he understood the charges, including the operation of a continuing criminal enterprise, conspiring to murder rivals, firearms violations and money laundering.
In a low voice, the defendant replied: "Si, Señor."
His arraignment in US District Court for the Eastern District of New York came one day after Guzman was quietly extradited from his native Mexico to the US.
Guzman's next court appearance was set for February 3.
"Who is Chapo Guzman?" US Attorney Robert Capers of the Eastern District of New York asked rhetorically while addressing reporters before the arraignment. "In short, he is a man who has known no other life than one of crime, violence, death and destruction."
Stringent security measures were put in place around the Manhattan jail where Guzman is to be held, a law enforcement source said. The Brooklyn Bridge will be closed while the drug lord is being transported to court.
Guzman, 59, is named in a sweeping 17-count indictment alleging that from 1989 to 2014 he led a continuing criminal enterprise responsible for importing and distributing massive amounts of narcotics and conspiring to murder rivals who posed a threat, according to Capers.
Guzman is also charged with firearm violations related to drug trafficking and money laundering connected to the smuggling from the United States to Mexico of more than $14 billion in cash from narcotics sales.
The charges carry a minimum sentence of life in prison, Capers said. Federal prosecutors also intend to seek a $14 billion criminal forfeiture order against Guzman.
He's no Robin Hood
"Guzman's story is not one of a do-gooder or a Robin Hood or even one of a famous escape artist who miraculously escaped from Mexican prisons on multiple occasions," Capers told reporters Friday.
The US attorney compared Guzman's "destructive and murderous rise" to "a small cancerous tumor that metastasized and grew into a full-blown scourge that for decades littered the streets of Mexico with the casualties of violent drug wars ... (and) helped to perpetrate the drug epidemic here in the US."
When Guzman got off of the plane in New York Thursday night, some law enforcement officers noticed a different demeanor than that his mythic persona.
"As you looked into his eyes you can see the surprise, you can see the shock, and to a certain extent you can actually see the fear as the realization started to kick in that he's about to face American justice," said Angel M. Melendez, special agent in charge for Homeland Security Investigations, New York.
Melendez also noted the tight security in place at the Manhattan jail, saying "no tunnel will be built leading to his bathroom." He was referring to Guzman's latest escape from a Mexican prison, when he slipped through a hole in the floor near his toilet and fled through a mile-long tunnel.
US officials: Extradition was a surprise
The extradition may have been timed. Mexican authorities wanted to turn over Guzman, head of the Sinaloa cartel, before Friday's inauguration of President Donald Trump, one US official told CNN. Trump angered Mexico during his campaign by demanding it pay for a border wall.
A Mexican deputy attorney general, however, said Trump's pending inauguration "had nothing to do with it."
"It was resolved today, and in terms of the international treaty, we had to immediately hand over the person requested by the United States," Alberto Elias Beltran said. "Not doing so would generate a nonfulfillment to the international norms, specifically with the treaty shared between Mexico and the United States."
US authorities said they "did not know" Guzman's extradition was going to happen Thursday, according to Deputy Assistant Attorney General Kenneth A. Blanco of the Justice Department's Criminal Division.
Officials were ready, because they had planned for it, but they were unaware it was going to happen Thursday, Capers said.
When asked whether the timing was politically motivated, authorities declined to speculate, and Blanco would not comment on any statements El Chapo may or may not have made.
Blanco also thanked several officials in Mexico for their cooperation, including President Enrique Peña Nieto, the secretary of foreign affairs and the attorney general.
"This extradition would not have been possible without the strong efficient close cooperation we have in our working relationship with our Mexican counterparts," he said.
DEA, ICE, US marshals pick up Guzman
Guzman, who was moved last year to Ciudad Juarez, was picked up by a team from the Drug Enforcement Administration, Immigration and Customs Enforcement and US marshals.
Six separate indictments across the United States lay out wide-ranging cases against Guzman and others, alleging they have brought in billions in drugs to the United States and laundered profits back to Mexico.
The extradition brings an end, at least for now, to Guzman's exploits in Mexico, which included a 2015 prison escape through a mile-long tunnel that featured a motorcycle on tracks.
Guzman will not face death penalty in US
A court in Mexico City on Thursday denied the drug lord's appeal of the extradition.
The US Justice Department thanked officials in Mexico "for their extensive cooperation and assistance in securing the extradition of Guzman ... to the United States."
Guzman and other cartel leaders were indicted in 2009 in US District Court in Brooklyn on charges of conspiring to import more than 264,000 pounds of cocaine into the United States between 1990 and 2005. The alleged traffickers are accused of sharing drug transportation routes and obtaining their drugs from Colombian drug organizations.
Guzman also faces charges in California, Texas, Illinois, Florida and New Hampshire. Mexico's foreign ministry has said it had received assurances that if convicted, Guzman would not receive the death penalty. Mexico opposes capital punishment.
Federal indictments described the Sinaloa cartel as an enterprise that uses murder, kidnappings and bribes.
The indictments refer to Guzman by various nicknames, including "El Rapido," "Papa," "El Viejo" and "El Chapo" (which means "Shorty." Guzman is 5 feet 6 inches tall.)
Over the years, Guzman gained near-mythic status in his home country. He has been the subject of ballads called "narcocorridos," a subgenre dedicated to cartels and their narco-violence.
Tunnels and a laundry cart getaway
Guzman was arrested in Guatemala in June 1993 and extradited to Mexico. Convicted on drug trafficking, murder and kidnapping charges, he was sentenced to a minimum of 20 years in a maximum security prison before his multiple escapes.
For years, the notorious cartel leader proved slippery, staying just ahead of the law. He is known for using intricate tunnel systems for both evading authorities and moving the massive quantities of drugs that made the Sinaloa cartel so powerful.
Guzman's recapture in January 2016, after six months on the lam, represented a major success in what has been an embarrassing ordeal for Mexico. For many, "El Chapo" is a symbol of the Mexican government's corruption.
In 2001, he escaped from a prison in Jalisco in a laundry cart. Guzman was apprehended in February 2014 and escaped from Altiplano prison in July 2015 by crawling through an opening in the shower area of his cell block leading to a mile-long tunnel.
In August, Guzman's son was kidnapped from a Puerto Vallarta restaurant in what was perceived as an attempt to exploit the cartel's vulnerability. He was later freed.
'El Chapo' said drug trade would continue
The trafficking of heroin, marijuana, cocaine and methamphetamine into the United States from Mexico is an annual $19 billion to $20 billion industry, according to a Department of Homeland Security report.
And the Sinaloa cartel has traditionally held a dominant share of that market, thanks to Guzman's sophisticated business strategies and Sinaloa's control of trafficking routes.
A US Customs and Border Protection report that analyzed seizure data along the border between 2009 and 2010 found that "the removal of key personnel does not have a discernable impact on drug flows" into the United States.
Guzman seems aware that drug trafficking won't end once he's gone. "The day I don't exist, it's not going to decrease in any way at all," he told actor Sean Penn in an interview in October 2015.