PHILADELPHIA -- A passenger train derailed in Philadelphia, Pennsylvania, on Tuesday night.
Train 188 was traveling from Washington, D.C., to New York City on Tuesday night when it derailed.
CNN is reporting at least 50 people were injured in the crash.
Word of the derailment quickly spread on social media, with posts on Twitter describing crews searching for wreckage and helicopters hovering overhead.
Video from CNN affiliates showed what appeared to be an overturned train car and people with flashlights searching the area.
Law enforcement tells WPVI the cause of the derailment may be a collision with a freight train or truck.
The NTSB issued a statement and said they are "currently gathering information about tonight's Amtrak derailment in Philadelphia."
Amtrak said they are "aware of the derailment of Northeast Regional train 188 north of Philadelphia and will provide updates as they become available."