Houston police were called to a house on the 4300 block of Spring Valley Drive near Brookshire Drive around 12:20 a.m. early Tuesday morning.
Officers found a 41-year-old man with a gunshot wound inside the home and was declared dead at the scene.
Police said that two men were visiting the tenants at the home when one of them pulled a gun and shot the other, then fled the scene in a white car.
A preliminary investigation and witness statements indicated the suspect is a person known to the victim, and possibly may have been a friend to the victim.
Anyone with information in this case is urged to contact the HPD Homicide Division at 713-308-3600 or speak anonymously to Crime Stoppers at 713-222-TIPS.